NSF/ANSI 455-2 Certification for Dietary Supplement Operations

What Is NSF/ANSI 455-2, Why It Matters, and How Our Experts Help You Get There

If your facility manufactures, packages, warehouses, or distributes dietary supplements, certification to NSF/ANSI 455-2 isn’t just a regulatory checkbox—it’s a strategic necessity. This GMP standard aligns with 21 CFR Parts 111 and 117, consolidating expectations from regulators, retailers, and global supply chain partners into one auditable framework.

It’s also the standard now recognized by Amazon for dietary supplement compliance—making it essential for facilities that support brands selling online.

Who Needs NSF/ANSI 455-2?

This certification applies to operations that:

• Manufacture dietary supplements (blending, encapsulation, tableting, etc.)
• Package finished products for retail or bulk distribution
• Warehouse raw materials or finished goods
• Distribute supplements to retailers, e-commerce platforms, or other facilities

Whether you’re a contract manufacturer, private labeler, or vertically integrated brand, NSF/ANSI 455-2 is the GMP standard that validates your systems.

What Makes NSF/ANSI 455-2 Distinct?

Unlike traditional GMP audits, NSF/ANSI 455-2:

• Is accredited—meaning it meets ISO/IEC 17065 standards for certification bodies
• Reduces audit fatigue by consolidating retailer and regulatory expectations
• Aligns with FDA requirements while offering third-party credibility
• Is accepted by Amazon and other major platforms for supplement listing approval
• Covers risk-based controls, sanitation, traceability, and quality systems in depth

It’s not just a pass/fail—it’s a blueprint for operational excellence.

How Our Consulting Team Helps

We specialize in helping facilities build systems that work—on paper, in practice, and under audit.

Certification Map: Your Path to NSF/ANSI 455-2

Step 1: Gap Assessment
We evaluate your current systems against NSF/ANSI 455-2 requirements and identify areas for improvement.

Step 2: Documentation Buildout
We help you develop or refine SOPs, records, and quality manuals tailored to your operations.

Step 3: Training & Implementation
We train your team—QA, production, leadership—on GMP expectations and audit behavior.

Step 4: Mock Audit & Corrective Actions
We simulate a third-party audit, identify gaps, and coach your team through corrective actions.

Step 5: Certification Support
We support you during the actual audit, helping you respond to findings and finalize documentation.

Whether you’re pursuing NSF/ANSI 455-2, SQF, FSSC 22000, or ISO 22000, we tailor our approach to your facility’s needs and your market’s demands.

Why It Matters

Certification isn’t just about compliance, it’s about trust.

It tells your customers, regulators, and partners that your operation is clean, controlled, and professionally managed. It protects your brand, opens doors to new markets, and ensures your systems are built to last.